Publications

The complete list of my publications can be found in PubMed.

Here is a selection of my recent and favorite work:

  • Novel citation-based search method for scientific literature: application to meta-analyses. ACJW Janssens, M Gwinn. BMC Med Res Methods 2015;15:84.
  • Returning pharmacogenetic secondary findings from genome sequencing: Let’s not put the cart before the horse. ACJW Janssens, JP Evans. Genet Med 2015;11:854-6.
  • Prediction impact curve was a new graphical approach integrating intervention effects in the evaluation of prediction model utility. W Campbell, A Ganna, E. Ingelsson, ACJW Janssens. J Clin Epidemiol 2016:69:89-95.
  • The hidden harm behind the return of results from personal genome services: A need for rigorous and responsible evaluation. ACJW Janssens. Genet Med 2015;17:621-2.
  • Personal utility in genomic testing: Is there such a thing? E Bunnik, ACJW Janssens, M Schermer. J Med Ethics 2015;41:322-6.
  • A critical assessment of discordant meta-analyses on reduced-function CYP2C19 genotype and risk of adverse clinical outcomes. R Osnabrugge, SJ Head, F Zijlstra, JM ten Berg, MGM Hunink, AP Kappetein, ACJW Janssens. Genet Med 2015;17:3-11.
  • Useless until proven effective – the clinical utility of preemptive pharmacogenetic testing. ACJW Janssens, P Deverka. Clinical Pharmacology and Therapeutics 2014;96:652-4.
  • Criteria for health checks: development of an European consensus agreement. M Bijlsma, A Rendering, N Chin-On, A Debska, L von Karsa, J Knopnadel, L van Rossum, ACJW Janssens. Prev Med 2014; 67C:238-241.
  • Naming and framing in genomic testing. E Bunnik, M Schermer, ACJW Janssens. Trends Mol Med 2014;20:63-5.
  • Raw personal data: access to inaccuracy. ACJW Janssens. Science 2014;343(6174):968.
  • Variations in predicted risks in personal genome testing for common complex diseases. R Kalf, R Mihaescu, S Kundu, P de Knijff, RC Green, ACJW Janssens. Genet Med 2014;16:85-91.
  • Estimating the predictive ability of genetic risk models using data from genome-wide association studies. S Kundu, R Mihaescu, C Meijer, R Bakker, ACJW Janssens. Front Genet 2014;5:179.
  • Research Conducted Using Data Obtained through Online Communities: Ethical Implications of Methodological Limitations. ACJW Janssens, P Kraft. PLoS Med. 2012;9:e1001328.
  • PredictABEL: an R package for the assessment of risk prediction models. S Kundu, YS Aulchenko, CM van Duijn, ACJW Janssens. Eur J Epidemiol 2011;26:261-4.
  • Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.ACJW Janssens, JPA Ioannidis, S Bedrosian, P Boffetta, SM Dolan, N Dowling, I Fortier, AN Freedman, JM Grimshaw, J Gulcher, M Gwinn, MA Hlatky, H Janes, P Kraft, S Melillo, CJ O’Donnell, MJ Pencina, D Ransohoff, SD Schully, D Seminara, DM Winn, CF Wright, CM van Duijn, J Little, MJ Khoury.  Eur J Hum Genet 2011;5:18.
  • Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. ACJW Janssens, JPA Ioannidis, CM van Duijn, J Little, MJ Khoury.  PlosMed 2011;8:e1000420.
  • Improvement of risk prediction by genomic profiling: reclassification measures versus the area under the receiver operating characteristic curve. R Mihaescu, M van Zitteren, M van Hoek, EJ Sijbrands, AG Uitterlinden, JC Witteman, A Hofman, MG Hunink, CM van Duijn, ACJW Janssens. Am J Epidemiol 2010;172:353-61.
  • An epidemiological perspective on the future of direct-to-consumer personal genome testing. ACJW Janssens, CM van Duijn. Investigative Genetics 2010;1:10.
  • A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions. ACJW Janssens, LA Bradley, M Gwinn, BA Oostra, CM van Duijn, MJ Khoury. Am J Hum Genet 2008;82:593-9.
  • Genome-based prediction of common diseases: advances and prospects. ACJW Janssens, CM van Duijn. Hum Mol Genet 2008:17;R166-73.
  • Predictive testing for complex diseases using multiple genes: fact or fiction? ACJW Janssens, YS Aulchenko, S Elefante, GJJM Borsboom, EW Steyerberg, CM van Duijn. Genet Med 2006;8:395-400.
  • Revisiting the clinical validity of multiplex genetic testing in complex diseases. ACJW Janssens, MC Pardo, EW Steyerberg, CM van Duijn. Am J Hum Genet 2004;74:585-8.